
Multi-specialty practices face a unique and complex set of challenges when it comes to revenue cycle management. With diverse service lines, varying payer rules, and complex coding requirements, managing the financial health of a multi-specialty group can feel like conducting a symphony orchestra where every musician is playing from a different sheet. The result is often a chaotic mix of claim denials, revenue leakage, and administrative overload.
This article explores the key challenges multi-specialty practices face and evaluates the best RCM software solutions designed to bring harmony to this complex environment. We will compare the top platforms and provide a clear guide to help you choose the right solution for your practice.
The Best RCM for Multi-Specialty Practices
Managing the revenue cycle in a single-specialty practice is difficult enough. In a multi-specialty environment, the complexity multiplies. Here are some of the top challenges these practices face:
These challenges contribute to significant lost revenue. The initial claim denial rate in healthcare reached 11.8% in 2024, and for complex multi-specialty claims, that number can be even higher.
To effectively manage these challenges, multi-specialty practices need an RCM solution that is both powerful and flexible. Here’s a look at three of the top contenders in 2025:
ENTER is designed to address the core challenges of multi-specialty practices with its unified, AI-first platform. By replacing fragmented systems with a single, end-to-end solution, ENTER provides a level of transparency and control that is difficult to achieve with a modular approach. Their reporting solutions provide a consolidated view of financials across all specialties.
Key Features for Multi-Specialty Practices:
With a 99.6% collection rate and a 40-day implementation, ENTER is an excellent choice for practices looking to maximize revenue and achieve a fast ROI.
Waystar is a well-established leader in the RCM space, offering a comprehensive suite of solutions that can be tailored to the needs of any practice. Their modular approach allows practices to select the specific tools they need to augment their existing systems, which can be an advantage for large organizations with complex IT infrastructure.
Key Features for Multi-Specialty Practices:
Waystar's recent acquisition of Iodine Software has further strengthened its AI capabilities, making it a powerful contender for multi-specialty practices.
athenahealth offers a unique value proposition by combining its EHR, athenaClinicals, with its RCM solution, athenaCollector. This tight integration creates a seamless workflow from patient registration to final payment, reducing the risk of data entry errors and improving overall efficiency.
Key Features for Multi-Specialty Practices:
For practices that are already using or considering athenahealth's EHR, their integrated RCM solution is a natural fit.

A unified RCM platform like ENTER can enforce standardized documentation and data entry protocols across all specialties. By creating a single, consistent workflow, the platform can significantly reduce the number of errors and omissions that lead to denials. For more on this, see the ENTER University for educational resources.
The cost of an RCM solution can vary widely depending on the size of the practice, the number of specialties, and the specific solutions being implemented. Most vendors, including ENTER, charge a percentage of collections, which typically ranges from 3% to 8%. For more specific information, check out the ENTER pricing page.
Implementation times can vary, but ENTER offers a rapid, 40-day onboarding process that is fully managed by their team. This includes custom EHR integration, clearinghouse configuration, and staff training.
For multi-specialty practices, achieving financial clarity requires a new approach to revenue cycle management. The old model of fragmented systems and manual processes is no longer sustainable in today's complex healthcare environment. By embracing a unified, AI-powered RCM platform, multi-specialty practices can not only survive but thrive.
While Waystar and athenahealth both offer strong solutions, ENTER stands out as the best choice for multi-specialty practices looking to maximize revenue, eliminate administrative burdens, and gain a clear, real-time view of their financial performance. With its unified platform, powerful AI engine, and industry-leading results, ENTER is the clear path to financial clarity.
Ready to bring harmony to your revenue cycle? Request a demo of ENTER today.